The study of the initiation and progression of cancers has seen an
active, and surprisingly successful involvement of mathematicians with
cancer research. Simple statistical models have long been known to be
able to account for the power-law age-specificity of cancer.
Evolutionary theory, has now been shown to be able to predict the
progression of certain cancers to metastasis. A third group of
mathematical theories, the quasi-species models, is believed to
account for the sensitivity of cancers to radiation. More recently,
physicists have become involved in cancer research, developing
continuum models to describe the onset of cancer metastasis. The talk
will review the different physical and mathematical models of cancer
metastasis in the context of the controversial Weinberg model for
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